Study the effect of piroxicam treatment for intrauterine insemination using density gradient for sperm preparation

Back ground: Endometrium contraction following intra-uterine insemination(IUI) was considered one of implantation failure causes.Aim the study: The primary purpose study to ascertain effect piroxicam treatment on pregnancy outcome six days intrauterine insemination. Materials and Methods: accomplished in High Institute for Infertility Diagnosis Assisted Reproductive Technologies, Al-Nahrain University through period from Nov. 2020 till Oct. 2021 .Forty infertile couples were selected randomly IUI divided into 20 couple treated with other not piroxicam. semen samples prepared by discontinuous density gradient. Results: There no significant differences regarding mean FSH level (p=0.769), LH level(p=0.79) prolactin (p=0.299), E2 (p=0.348) TSH (p=0.950)between studied groups. difference dominant follicles counts, follicular sizes or endothelial thickness between two results showed a improvement sperm motility morphology (p < 0.05) after vitro activation gradient technique compared before activation. In group ,4 out women became pregnant while non-piroxicam ,3 spouses 15%when used.